Nucleofill is a biostimulation treatment injectable, designed to stimulate new collagen production in the dermis of the skin, to rejuvenate areas of skin laxity which can lift and tighten skin.

Nucleofill Soft Eyes is an alternative to tear trough filler and helps decrease lower eyelid puffiness, fine lines, wrinkles and volume loss.  This treatment is safe on all skin types.  This treatment can be done in combination with other treatments.

At A Glance

Procedure Time

30 minutes

Full Recovery

1-2 days

Back To Work



1 Month-9 months



Duration of Results

Up to a year *

Find out more about Nucleofill

Read the answers to the most commonly asked questions below. Or, book a consultation with one of our specialists and we’ll be happy to talk you through it.


Nucleofill is a next-generation biostimulation treatment that is injected to stimulate production of new collagen and elastin in the dermis of the skin and actively soften the signs of ageing in decreasing the appearance of fine lines and plump the skin.  Nucleofill can also be injected in the scalp where it may improve blood supply and hair growth over time.

Nucleofill is made from high molecular weight polynucleotide chains, which act to stimulate dermal fibroblast cells to increase production of collagen and elastin. Polynucleotides are highly viscoelastic, meaning that the skin will regain its ‘bounce’ quickly. The treatment involves injection at several points in the target area, from which the product spreads to treat the dermis over the entirety of the region, much like Profhilo.

Nucleofill provides deep skin hydration, smoothing of fine lines and wrinkles, boosting of collagen and elastin levels and dermal remodelling over time. Your complexion will appear healthy, hydrated and glowing with improved elasticity.

Any areas of the body can be treated with Nucleofill, the most popular areas being the face and neck.  Nucleofill hair can be used to improve scalp health and over time may enhance hair growth. Nucleofill soft can be used directly around the eyes to improve areas of skin laxity and crepeyness around the eyes.

There’s very minimal downtime with Nucleofill. There are often raised bumps from the injection points but these subside within a few hours. There is a small risk of bruising and/or swelling after any injectables. To reduce the risk of bruising we suggest that you avoid omega-3 fatty acid supplements, blood thinners and alcohol for 48 hours prior to your injectable treatments.

The advised treatment schedule is 2-3 treatments, two weeks’ apart, then repeat this every 6-9 months. More sessions can be done without risk, indeed we often see patients once every three months as an alternative to the conventional treatment schedule.

Nucleofill treatment costs £300 individually

A course of 2 sessions:£550

A course of 3 sessions: £675

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Before & After*

*Results may vary. These are dependent on a number of factors such as age, medical history and lifestyle.